Northwest Alabama Airport (MSL) | Hotels near the airport

The Comfort Inn & Suites® in Tuscumbia is the perfect place to enjoy everything the Shoals area has to offer. Located at the intersection of Highway 20 and Highway 43, our smoke-free hotel is convenient for business travelers and vacationers. You’ll find friendly service and cozy accommodations, all in a modern hotel with the amenities you care about.

Red Roof Inn Muscle Shoals is centrally located in the heart of Muscle Shoals and is only minutes away from local attractions and family dining. We are also near the Tennessee River, the Belle Mont Mansion and Spring Park.

Clarion Inn® Sheffield Muscle Shoals is just around the corner from all top Muscle Shoals area attractions. Being located in Sheffield, music is at the heart of our hotel. Enjoy an onsite entertainment venue, Fizz Sheffield, with entertainment every week and a delicious menu crafted by Chef Willie Thompson that pays tribute to the Shoals music scene.

Refresh and reenergize at our Days Inn by Wyndham Muscle Shoals Florence hotel near Lake Wilson. Located on U.S. Highway 72/43, our comfortable, quiet hotel is a great home base for exploring Alabama.

Located off US 72 in the Shoals area of Florence, we’re a short walk from shops, restaurants, and the historic district. Visit the Civil War hospital at Pope’s Tavern Museum, and the University of North Alabama, both under a mile away. We’re less than 15 minutes from Helen Keller Birth Place and the Alabama Music Hall of Fame. Enjoy daily free hot breakfast, WiFi, and our indoor pool.